*Registrants will be e-mailed a WebEx link approximately two days prior to the session. The District of Columbia is at the center of an opioid epidemic with fatal drug overdoses increasing by over 200% from 2014- 2017. To address these often fatal consequences of the opioid crisis, the District has implemented a multi-disciplinary response, identifying best practices and strategies for communities in addressing this epidemic. The presenter will provide a broad epidemiological profile of fatal and non-fatal opioid overdoses, a summary of the pharmacology of opioids and appropriate responses to emergency overdoses.